OBJECTIVE To review mechanism research progress of ganoderan antitumor.METHODS At the foundation of research literature of domestic and abroad,the different kinds of antitumor mechanism of ganoderan were summaried. RESULTS AND CONCLUSION Now,polysaccharides become a research hotspot as antitumor immunomodulator. The study reviewed mechanism of ganoderan antitumor at different fields: elevating the immune function of host,inhibiting tumor cell proliferation and metastasis,anti-oxidant,clearing oxygen radicals,increasing the expression of tumor MHC and costimulatory molecules,inducing tumor cell differentiation. The study also observed the existent problem of ganoderan research.
LI Xiao-bing,XIE Zhong-li,ZHU Yan-qin,CHEN Yu-long.
Research Progress of the Ganoderan Antitumor Mechanism[J]. Chinese Pharmaceutical Journal, 2013, 48(16): 1329-1332 https://doi.org/10.11669/cpj.2013.16.001
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